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Marlins at Pirates odds, picks and predictions

The Miami Marlins (24-39) and the Pittsburgh Pirates (26-40) open a 3-game series Monday. First pitch from PNC Park is at 6:40 p.m. ET (FS1). Let’s analyze BetMGM Sportsbook’s MLB odds around the Marlins vs. Pirates odds and make our expert MLB picks and predictions for the best bets.

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Season series: Marlins lead 2-1

The Marlins dropped 2 of 3 at the Tampa Bay Rays over the weekend and have lost 6 of their last 7. In Sunday’s 3-2 series finale loss, RP Valente Bellozo gave up a 2-run homer to 1B Yandy Diaz in the fifth, and RP Calvin Faucher later surrendered a go-ahead sacrifice fly in the eighth. DH Heriberto Hernandez went 3-for-3 with a run scored in the losing effort.

The Pirates are coming off a 3-game home sweep of the Philadelphia Phillies and have won 4 of their last 5. SP Paul Skenes was dominant again in Sunday’s 2-1 win, allowing just 2 hits and 1 unearned run over 7 2/3 innings while striking out 7. He didn’t factor into the decision, as DH Andrew McCutchen delivered the go-ahead RBI single in the eighth after Skenes was relieved by RP Braxton Ashcraft, who earned his first win of the season.

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ESPN+ $11.99/month USA
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StreamLocator 7-day free trial, no credit card required! $9.90/month Worldwide
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Marlins at Pirates projected starters

RHP Eury Perez vs. RHP Mike Burrows

Perez (5-6, 3.15 ERA in 2023) is making his 2025 debut and his first start since 2023 following Tommy John surgery. He had a 1.13 WHIP, 3.1 BB/9 and 10.6 K/9 in 91 1/3 innings across 19 starts as a 20-year-old rookie in 2023.

  • Last start vs. Pirates: Win, 6 IP, 0 ER, 4 H, 1 BB, 9 K in 2-0 home victory June 25, 2023
  • 2025 minor league stats: 1-1, 1.99 ERA (22 2/3 IP, 5 ER), 1.15 WHIP, 10.7 K/9 in 8 starts

Burrows (1-1, 5.27 ERA) makes his fourth start. The rookie has allowed 14 hits and 4 walks with 11 K’s through 13 2/3 innings.

  • Last start: Win, 5 1/3 IP, 0 ER, 5 H, 0 BB, 6 K in 3-0 home victory over Houston Astros Wednesday
  • Has never faced Marlins

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FuboTV 5-day free trial, $10–$90/month USA, Canada, Spain
ESPN+ $11.99/month USA
Fanatiz €6.99–€10.99/month Worldwide
StreamLocator 7-day free trial, no credit card required! $9.90/month Worldwide
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Marlins at Pirates odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:15 p.m. ET.

  • Moneyline (ML): Marlins -105 (bet $105 to win $100) | Pirates -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Marlins -1.5 (+165) | Pirates +1.5 (-200)
  • Over/Under (O/U): 8 (O: -118 | U: -102)

Marlins at Pirates picks and predictions

Prediction

Pirates 4, Marlins 2

The Marlins are only 10-19 on the road this season and have lost their last 5 series openers.

The Pirates are 17-18 at home and 8-5 in their last 13 games at PNC Park. They have held opponents to 3 or fewer runs in 7 of their last 10 games.

Burrows was sharp in his last outing, while Perez is set to make his 2025 debut and likely won’t pitch deep into the game.

BET PIRATES (-115).

You get better odds playing the Pirates straight up than taking their run line at -200.

PASS.

Two of the 3 meetings did not reach 8 total runs.

Seven of the Marlins’ last 9 games and 6 of the Pirates’ last 9 have stayed under 8 total runs.

BET UNDER 8 (-102).

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